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Our Work
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Together against CF we have successfully:
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![pGM169 (CpG free) 6549bp](https://static.wixstatic.com/media/a27d24_2a2f126720444e7fad34a5f9526dc05f~mv2.jpg/v1/fill/w_61,h_62,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/a27d24_2a2f126720444e7fad34a5f9526dc05f~mv2.jpg)
Start of the product evaluation study to assess the effectiveness of multiple gene transfer agents (GTAs) in pre-clinical studies.
![pGM169 GL67](https://static.wixstatic.com/media/851fc6_8aea2c571e8b4e6195e9f1bcd93b9dd3~mv2.jpg/v1/fill/w_88,h_62,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/851fc6_8aea2c571e8b4e6195e9f1bcd93b9dd3~mv2.jpg)
![Staged nebuliser delivery](https://static.wixstatic.com/media/851fc6_3e8159edbeb64d0587cb1285f3a5acc4~mv2.jpg/v1/fill/w_42,h_63,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/851fc6_3e8159edbeb64d0587cb1285f3a5acc4~mv2.jpg)
In preparation for the multi-dose trial, we designed a study of almost 200 people with cystic fibrosis. The purpose of this study was to help design the multi-dose trial and to choose the patients most likely to be able to demonstrate benefit.
![Pharmacist mixing GL67](https://static.wixstatic.com/media/851fc6_e0c24cbeb6904fff81c47816c7dd0ab6~mv2.jpg/v1/fill/w_94,h_63,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/851fc6_e0c24cbeb6904fff81c47816c7dd0ab6~mv2.jpg)
We recruited ~130 people with CF (aged 12 years and above) into the trial. The trial was a blinded, placebo-controlled study, meaning that each participant had a 50:50 chance of receiving gene therapy or 'dummy' treatment, with neither participants nor investigators knowing which.
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